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In addition, participants were not informed that treatment was available for their disease after antibiotics had been developed.One of the most famous teachers at Tuskegee was George Washington Carver, whose name is synonymous with innovative research into Southern farming methods and the development of hundreds of commercial products derived from regional crops, including peanuts and sweet potatoes.Beginning in 1932, the school was the site of the now-infamous Tuskegee syphilis experiment (1932–1972), started to test treatments of the disease.With funding cut by the Great Depression, the Institute staff cut back on medications to treat the disease and studied the effects of untreated syphilis on patients and their partners.Washington believed that African Americans would achieve acceptance by southern whites when they had raised themselves.Washington led the school for decades, building a wide national network of white industrialist donors among some of the major philanthropists of the era, including George Eastman.The area was settled by European Americans in the 1830s after the Creek Native American tribes had been removed to Indian Territory west of the Mississippi River.Pioneer planters brought or purchased African-American slaves to develop the rich soil for cotton plantations, as short-staple cotton was the chief commodity crop through the 19th century.

After the war, many freedmen continued to work on plantations in the rural area, which was devoted to agriculture.

In 1923, the Tuskegee Veterans Administration Medical Center was established here, initially for the estimated 300,000 African-American veterans of World War I in the South, when public facilities were racially segregated.

Twenty-seven buildings were constructed on the 464-acre campus.

In 1881 the Tuskegee Normal School (now Tuskegee University, a historically black college) was founded and its director, Booker T.

Washington developed a national reputation and philanthropic network to support education of freedmen and their children.

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Some 3,000 African-American residents protested passage of the law at a church in Tuskegee; they also began an economic boycott of white businesses in the city.

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